Basically, this question is aimed at finding out whether you are good with some kind of authority above you or whether you are someone who requires a mentor. Your response may also cause the interviewer to view you as an optimistic or complaining type, so tread carefully.

The best answer is to speak of the cordial aspects of the relationship you enjoyed with your supervisor. If you must mention any issues, be brief, and downplay any problems. For example, explain how any differences you had were purely theoretical and in the end, what was best for the company won. Of course if this is not so, explain the difficulties and how you overcame them. End with an encouraging example of getting along.