► Change in eating habits

► Change in sleeping habits, fatigue

► Feelings of pessimism or hopelessness

► Restlessness, anxiety or irritability

► Feeling of guilt, helplessness or worthlessness

► Loss of interest in activities once enjoyed, including sex and hobbies

► Thoughts of suicide or attempts at suicide

► Physical aches or pains such as headaches or gastrointestinal upset that don't respond to treatment.